Amira Awadalla Mohammed lahlouba, PhD

Fellow of cell biology
Urology and Nephrology Center, Mansoura University
Talha, Mansoura, Egypt


Biography

Amira Awadalla received her first degree as BSc in Zoology and Chemistry in 2002 from Faculty of Science, Mansoura University. She worked in urology and nephrology center as a Specialist Medical tests at 2003, then as a Molecular Biologist till 2012 and from 2012 to 2015 as a Technical Director for Laboratory of Molecular biology research than a technical director of the center of excellence for genome and cancer research. She moved on to her MSc in Cytology, Histochemistry& Genetics Faculty of science, Zagazig University in 2011. Also, she got a diploma in microbiology, 2012, Faculty of Mansoura University. She obtained her PhD on genetic, 2014, Faculty of science Zagazig University and now she is a fellow of cell biology, histology, and genetics.

Research Interest

• Renal Physiology.
• Renal Ischemia/Reperfusion Injury.
• Stem cell therapy in Ischemia/Reperfusion Injury.
• Pathogenesis of Bladder cancer
• Diagnostic and prognostic biomarker in bladder cancer
• Bladder cancer stem cell.
• Chromosomal instability of Hepatitis C virus (HCV).

Scientific Activities

Publications

1. Shokeir AA, Barakat N, Hussein AA, Awadalla A, Abdel-Aziz A, Abo-Elenin H. Role of combination of L-arginine and α- tocopherol in renal transplantation ischaemia/ reperfusion injury: a randomized controlled experimental study in a rat model. BJU Int. 2011 Aug;108(4):612-8. doi: 10.1111/j.1464-410X.2010.09943.x. Epub 2011 May 18
2. Shokeir AA, Hussein AA, Soliman SA, Kamal MM, Abdel-Aziz A, Awadalla A, Rahim MA, Barakat N. Recoverability of Renal Functions after Relief of Partial Ureteral Obstruction of Solitary Kidney: Impact of Ferulic Acid. BJU Int. 2012 Sep;110(6):904-11. doi: 10.1111/j.1464-410X.2011.10848.x. Epub 2012 Mar 1.
3. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Ahmed A. Shokeir. Systemic and Renal Haemodynamic Changes in Renal Ischemia/Reperfusion Injury: Impact of Erythropoietin. Can J Physiol Pharmacol. 2012 Nov;90(11):1535-43. doi: 10.1139/y2012-120. Epub 2012 Nov 8.
4. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Ahmed Samy, Azza Abdelaziz, Sheiri Khater , Nashwa Barakat. Protection against Renal Ischemia/ Reperfusion Injury: A Comparative Experimental Study of the impact of Ischemic Preconditioning versus Postconditioning. Arab J of Urology 10 (4): 418-424, 2012.
5. Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza Abdel-aziz, Ahmed A Shokeir, Ahmed S El-Hefnawy, and Hassan Abol-enein. Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer. Infect Agent Cancer. 2013 Jun 28;8(1):24. doi: 10.1186/1750-9378-8-24.
6. Ahmed A. Shokeir, Abdelaziz M. Hussein, Amira Awadallah, Azza Abdelaziz, Nashwa Barakat. Activation of Nrf2 gene and its dependent genes by ischemic preconditioning and postconditioning. Acta Physiol (Oxf). 2013 Sep 7. doi: 10.1111/apha.12164
7. Kamel Zaki Hemmaid, Amira Awadalla, Hassan Aboelenin, Abdelaziz M. Hussein, EssamElsawy, Mai B Mohammed, Abd El-Rahman, Nabawy Zekri Microsatellite Chromosomal Instability in Bladder Cancer Patients Infected with Hepatitis C Virus. IJSR - INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH. 2014; vol 3(9): 2277 - 8179
8. Ahmed A. Shokeir, Nashwa Barakat, Abdelaziz M. Hussein, Amira Awadalla, Ahmed Harraz, Shery Khater, Kamel Hemmaid. Activation of Nrf2 by Ischemic Preconditioning and Sulforaphane in Renal Ischemia/Reperfusion Injury: A Comparative Experimental Study. Physiol Res. Article in press, 2014
9. Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza Abdel-aziz, Ahmed A Shokeir, Ahmed S El-Hefnawy, and Hassan Abol-enein. Pattern of DNA Hypermethylation of APC, P16, P73, P16, O6MMGT, CD99 and CDH1 Genes in Bladder Cancer with Hepatitis C Viral (HCV) Infection. International Journal of Cancer Research, 05/2015; 49(1):1690-1703.
10. Mohamed H Zahran, Abdelaziz M. Hussein, Ahmed Harraz, Amira Awadalla, Nashwa Barakat, Shery Khater, Ahmed A. Shokeir. Sildenafil Activates Antioxidant and Antiapoptotic Genes and Inhibits Proinflammatory Cytokines Genes in A Rat Model of Renal Ischemia/Reperfusion Injury. Intern J nephrol and urol. 2015 Nov;47(11):1907-15. doi: 10.1007/s11255-015-1099-5. Epub 2015 Sep 16.
11. Abdelaziz M. Hussein, Ahmed Harraz, Amira Awadalla, Nashwa Barakat, Shery Khater, Ahmed A. Shokeir. Remote limb ischemic preconditioning (rIPC) activates antioxidant and antiapoptotic genes and inhibit proinflammatory cytokine genes in renal ischemia/reperfusion injury. J Physiology and Biophysics 2016 Jan;35(1):77-86. doi: 10.4149/gpb_2015035. Epub 2015 Nov 27.
12. Abdelaziz M. Hussein, Nashwa Barakat, Amira Awadalla, Mahmoud M. Gabr, Sherry Khater, Ahmed M. Harraz, and Ahmed A. Shokeir Modulation of renal ischemia/reperfusion in rats by acombination of ischemic preconditioning and adipose-derived mesenchymal stem cells (ADMSCs). Can. J. Physiol. Pharmacol. 94: 1–11 (2016).
13. Hassan Aboel-enein, Abdelrhaman N. Zekri, Abdel-aziz M. Hussein, Amira Awadalla , Amira ALHawari , Sherry Khater , Kamel Z. Hemmaid, Mai Bakr, Ahmed A. Shokeir. Molecular Profiling of Early Stage Bilharzial Bladder Cancer in Egypt by cDNA Microarray. International Journal of Cancer Research.
14- Ahmed R. El-Nahas*, Mohamed M. Elsaadany*, Diaa-Eldin Taha*, Ahmed M. Elshal*, Mohamed Abo El-Ghar†, Amani M. Ismail‡, Essam A. Elsawy§, Hazem H. Saleh§, Ehab W. Wafa¶, Amira Awadalla**, Tamer S. Barakat* and Khaled Z. Sheir* .A randomised controlled trial evaluating renal protective effects of selenium with vitamins A, C, E, verapamil, and losartan against extracorporeal shockwave lithotripsy-induced renal injury. BJU Int 2017; 119: 142–147
15- Mansour, A.M., Abdelrahim, M., Laymon, M. ,Elsherbeeny, M.,Sultan, M., Shokeir, A. ,Mosbah, A., Abol-Enein, H., Awadalla, A.,Cho, E. ,Sairam, V., Park, T.D., Shahid, M. and Kim,J. Epidermal growth factor expression as a predictor of chemotherapeutic resistance in muscle-invasive bladder cancer. BMC urology 2018;18(1):100

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