Dr. Marzia Cottini

Surgery and Heart transplantation Center

C. De Gasperis,  Niguarda Hospital, Milan



Dr. Marzia Cottini holds a Doctorate in Medicine from the University of Varese (in Italy). Afterwards, she attended the cardiac surgery residency program in Varese and the last months at the Toronto General Hospital (Toronto, Ontario, Canada). She obtained the Postgraduate Specialization in Cardiac Surgery in May 2015. She had attended a surgical and research fellowship in cardiac surgery at the Heart Transplantation Center of San Camillo Hospital ( Rome, Italy) and then a surgical fellowship at the Cardiac Surgery Department of the La Pitie-Salpetriere ( Paris, France). Currently, she is attending the PhD course of Angio-Cardio-Thoracic Pathophysiology and Imaging, University "La Sapienza" (Rome, Italy). Recently, I have started to work as Cardiac Surgeon at the Niguarda Hospital of Milan, Italy.

Research Interest

Cardiac Surgery, Heart transplantation, Heart failure, current therapy in heart failure, future perspectives in angio-cardio-thoracic imaging.

Scientific Activities


2010 Grant Lions club, Medical Degree Grant, Lion Society Varese, Italy
05/2016 Grant "Eccellenze in Sanità 2016: San Camillo-Forlanini", Excellence in the Italian Health 2016, section "Young people build the future", Rome, Italy
10/2016 Grant " Borsa di studio trimestrale di approfondimento clinico/chirurgico suitrapianti d'organo presso Centri Trapianto esteri (Quarterly scholarship of clinical / surgical study on organ transplants in foreign transplantation centers)". SITO Italian Society of Organ Transplantation, Rome, Italy
11/2016 Grant "Silvia Salvati", Italian Cardiac Surgery Society, Rome, Italy
08/2017 Classified for the "Young Investigators Awards", ESC Congress 2017 (Barcelona, 08/2017) with the project: " Cardiac allograft vasculopathy: new perspective in diagnostic workout"

Internship/ Observership/Fellowship:
2004 Internship in Biochemistry and Medical Research at the Biochemistry Department, Faculty of Medicine and Surgery, University Insubria of Varese (Italy).
Internship in Immunohematology and Transfusion Medicine, Faculty of Medicine and Surgery, at the University Hospital of Varese (Italy).
2005 Internship Management an Ambulatory for diagnosis and care of the Hypertension, Faculty of Medicine and Surgery, University Insubria of Varese (Italy).
Internship in Internal Medicine at the University Hospital of Varese (Italy).
Internship in Vascular Surgery at the University Hospital of Varese (Italy).
Internship in Cardiac Surgery at the University Hospital of Varese (Italy).
Internship in General Surgery at the University Hospital of Varese (Italy).
2010- 2015 Resident (5th year), Cardiac Surgery Department, University Hospital Circolo, Fondazione Macchi Varese, Italy
2014- November Observership in CardioVascular Department, San Camillo Forlanini, (Heart and Lung Transplantation Center), Under the supervision of Prof. F. Musumeci, Rome, Italy.
2015 January- March Elective Observership in Cardiovascular Surgery Department, Toronto General Hospital, Toronto, Ontario, Canada, under the direct supervision of Dr. T. David, Dr. R. Cusimano and Dr. V. Rao.
2015 March Observership in Pediatric Cardiac Surgery Labatt Family, Sick Children Hospital Toronto, Ontario, Canada, under the direct supervision of Dr. Van Arsdell.
2017 February-May Clinical Fellowship in Cardiovascular Surgery Department, Groupe Hospitalo-Universitarie Pitiė-Salpetriere-Charles Foix,, Institute de Cardiologie, Paris (France), under the direct supervision of Prof. Pascal Laprince.

Membership of Institutes and Societies:
Member of Società Italiana di Chirurgia Cardiaca ( SICCH: Italian Society of Cardiac Surgeon, since 2009)
Member of European Association of Cardio-Thoracic Surgery (EACTS, since 2009)
Member of AIRC: Associazione Italiana per la Ricerca sul Cancro (AIRC: Italian Cancer Research Society, since 2009)
Member of STS (American Society of Thoracic Surgeons, since 2013)
Member of AHA (American Heart Association, since 2014)
Member of ANMCO ( Associazione Italiana Medici Cardiologi Ospedalieri)
Member of ANMCO Heart Failure National Work Group (since May 2016)
Member of SITO (Società Italiana Trapianti d'Organo, Italian Society of Organ Transplantation, since April 2016)
Member of European Society of Cardiology
Member of Heart Failure Association of the ESC (since May 2016)
Fellow Cardiac Surgery field, ANMCO (Italian Hospital Cardiologist Society)
Member of ESC Working Group "Valvular Heart Disease" (since 24/4/2017)
Member of ESC Working Group "Pericardial and Myocardial Disease" (since 06/2017)
Member of ESC Working Group "Cardiovascular Surgery" (since 11/2017)


1. Mariscalco G., Bruno VD, Cottini M., Borsani P., Banach M., Piffaretti G, Dominici C, Beghi C, Sala A. “Optimal timing of discontinuation of clopidogrel and risk of blood transfusion after coronary surgery. Propensity score analysis”. Circulation Journal 2011;75(12):2805-12. Epub 2011 Oct 22.
2. Giovanni Mariscalco, MD, PhD, Marzia Cottini, MD, Marco Zanobini, MD, Stefano Salis, MD, Maciej Banach, MD, PhD, Gabriele Piffaretti, MD, PhD, Giovanna Covaia, MD, Marco Realini, MD, Cesare Beghi, MD, and Andrea Sala, MD “Preoperative statin therapy is not associated with a decrease in the incidence of delirium after cardiac surgery: a propensity score analysis” (Ann Thorac Surg. 2012 May;93(5):1439-47).
3. Lorusso R, Gelsomino S, Vizzardi E, D'Aloia A, De Cicco G, Lucà F, Parise O, Gensini GF, Stefàno P, Livi U, Vendramin I, Pacini D, Di Bartolomeo R, Miceli A, Varone E, Glauber M, Parolari A, Giuseppe Arlati F, Alamanni F, Serraino F, Renzulli A, Messina A, Troise G, Mariscalco G, Cottini M, Beghi C, Nicolini F, Gherli T, Borghetti V, Pardini A, Caimmi PP, Micalizzi E, Fino C, Ferrazzi P, Di Mauro M, Calafiore AM; ISTIMIR Investigators; Mitral valve repair or replacement for ischemic mitral regurgitation? The Italian Study on the Treatment of Ischemic Mitral Regurgitation (ISTIMIR). J Thorac Cardiovasc Surg. 2013 Jan;145(1):128-39; discussion 137-8. doi: 10.1016/j.jtcvs.2012.09.042;
4. Giovanni Mariscalco, MD, PhD, Marzia Cottini, MD, Carmelo Dominici, MD, Maciej Banach, MD, PhD, Gabriele Piffaretti, MD, PhD, Paolo Borsani, MD,PhD, Bruno Vito Domenico, MD, PhD, and Cesare Beghi, MD; The Effect of Timing of Cardiac Catheterization on Acute Kidney Injury after Cardiac Surgery is Influenced by the Type of Operation. Int J Cardiol. 2014 Feb 20. pii: S0167-5273(14)00363-5. doi: 10.1016/j.ijcard.2014.02.010;
5. Mariscalco G, Biancari F, Zanobini M, Cottini M, Piffaretti G, Saccocci M, Banach M, Beghi C, Angelini GD. Bedside Tool for Predicting the Risk of Postoperative Atrial Fibrillation After Cardiac Surgery: The POAF Score. J Am Heart Assoc. 2014 Mar 24;3(2):e000752. doi: 10.1161/JAHA.113.000752.
6. G. Mariscalco, F. Biancari, T. Juvonen, M. Zanobini, M. Cottini, M. Banach, G. J. Murphy, C. Beghi and G. D. Angelini. "Red blood cell transfusion is a determinant of neurological complication after cardiac surgery". Interactive Cardiovascular and Thoracic Surgery, 20 (2015)166-171.
7. F. Biancari, F. Onorati, A. S. Rubino, M.A. Mosorin, T. Juvonen, N. Ahmed, G. Faggian, C. Mariani, C. Mignosa, M. Cottini, C. Beghi e G. Mariscalco. Outcome of Emergency Coronary Artery Bypass Grafting. Journal of Cardiothoracic and Vascular Anesthesia, 2015, Vol. 29, Issue 2, p275–282.
8. G. Piffaretti, M. Cottini, G.P. Carrafiello, P.Castelli, C. Beghi and G. Mariscalco. Endovascular repair of Ascending Aortic Pseudoaneurysm with Custom-Designed Endograft. Ann Thorac Surg 2015; 100: e31-3.
9. Cottini M, Pergolini A, Gentile P, Musumeci F. Primary Cardiac Angiosarcoma. J Card Surg 2016;31:63–64. doi: 10.1111/jocs.12672.
10. Marzia Cottini, Marco Picichè, Amedeo Pergolini, Tania Dominici and Francesco Musumeci, "A Review of myasthenia gravis in cardiac surgery", J Integrat Card 2015, Volume 2(1): 232-235. doi: 10.15761/JIC.1000145.
11. Giangiuseppe Cappabianca, M.D.; Giovanni Mariscalco, Ph.D., M.D.; Fausto Biancari, Ph.D., M.D; Daniele Maselli, M.D.; Francesca Papesso, M.D.; Marzia Cottini, M.D.; Sandro Crosta, M.D.; Simona Banescu, M.D.; Aamer B. Ahmed, B.M.B.S, F.R.C.A., F.A.C.C., F.E.S.C.; Cesare Beghi, M.D. Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery. Critical Care 2016, 20:5, DOI: 10.1186/s13054-015-1172-6.
12. Cottini M, Terrieri F, Piffaretti G, Beghi C. Fatal Basilar Arterial thrombosis after cardiac surgery: case report and review of the literature. ARC Journal of Anesthesiology Volume 1, Issue 1, 2016, 17-21.
13. Cottini M, Pergolini A, Picichè M, Musto C, Musumeci F. Life hanging by a thread. Polska Heart Journal, Kardiologia Polska 2016; 74, 10: 1; DOI: 10.5603/KP.2016.
14. Cottini M, Dominici T, Sbaraglia F, Pergolini A, Di Stefano G, Polizzi V, Feccia M, Buffa V, Lilla Della Monica P, Musumeci F. Future perspectives in Cardiac Allograft Vasculopathy. Asian Journal of Science and Technology, Vol.07, Issue, 04, pp.2703-2707, April, 2016.
15. Marzia Cottini, Vincenzo Polizzi, Paolo G. Pino, Vitaliano Buffa, Francesco Musumeci, Transesophagheal echocardiography and Radiation-Induced damages. Heartviews, Vol 17, Issue 3, Jul-Sep 2016: 114-6.
16. F. Terrieri, M. Cottini, M. Picichè, S. Rausei, C. Beghi, Isolated Celiac Trunk after Cardiac Surgery. Journal of Surgery [Jurnalul de chirurgie]. 2016; 11(4): 131-137 DOI:10.7438/1584-9341-12-1-12
17. S. Donfrancesco, M. Cottini, A. Lappa, C. Nencini, P. Picozzi, F. Sbaraglia, V. Polizzi, P. Lilla Della Monica, A. Ricotta, A. Menichetti, F. Musumeci, Cabergoline, Levosimendan and Iabp: Treatment of Peripartum Cardiomyopathy. ARC Journal of Anesthesiology, Volume 1, Issue 2, 2016, PP 1-5, ISSN No. 2455-9792(Online), http://dx.doi.org/10.20431/2455-9792.010200
18. Marzia Cottini MD, Francesco Terrieri, G. Piffaretti MD, C. Beghi. Large posterior ascending aortic pseudoaneurysm 10 years after cardiac surgery. The Journal of Middle East and North Africa Sciences 2016; 2(8), 10-12.
19. Marzia Cottini, Amedeo Pergolini, Francesco Terrieri and Cesare Beghi, Atypical Complications of Huntington Chorea Disease. Journal of Cardiovascular Pharmacology: Open Access. Cardiovasc Pharm Open Access 2016, 5:4 http://dx.doi.org/10.4172/2329-6607.1000188.
20. Angela Lappa, Marzia Cottini, Silvia Donfrancesco, Carlo Contento, Antonio Menichetti, Francesco Musumeci. SINGLE O DOUBLE CANNULA FOR VENO-VENOUS ECMO IN SEVERE OBESE PATIENT: case report and review of the literature. ARC Journal of Anesthesiology, Volume 1, Issue 4, 2016, PP 19-24.
21. Marzia Cottini, Amedeo Pergolini, Giordano Zampi, Vitaliano Buffa, Paolo Giuseppe Pino, Vincenzo Polizzi, Federico Ranocchi, Giampaolo Luzi, Andrea Montalto, Francesco Musumeci. Posterior wall as atypical localization of left atrial myxoma: diagnosis and management. Herz, online first publication DOI 10.1007/s00059-016-4480-y
22. Marzia Cottini, Amedeo Pergolini, Francesco Musumeci, ASD Occluder Dislocation Engaged the Tricuspid Valve: Surgical Removal Through Right Thoracotomy, Polska Heart Journal, Kardiologia Polska 2016, Kardiol Pol. 2017;75(3):279. doi: 10.5603/KP.2017.0052.
23. Amedeo Pergolini, Marzia Cottini, Andrea Montalto, Giordano Zampi, Francesco Musumeci. Inverted left appendage: an unexpected echocardiographic image finding after left ventricular assist device implantation, Journal of Echocardiography, DOI: 10.1007/s12574-016-0326-0, J Echocardiogr. 2016 Dec 24. doi: 10.1007/s12574-016-0326-0.
24. Marzia Cottini, Amedeo Pergolini,, Giordano Zampi, Vitaliano Buffa, Paolo Giuseppe Pino, Federico Ranocchi, Riccardo Gherli, De Marco Marina, Carlo Contento, Myriam Lo Presti, Francesco Musumeci. Submitral Ventricular Pseudoaneurysm: unusual and late complication of cardiac surgery. Heighpubs Anesth Clin Res. 2017; 1: 001-004.
25. Marzia Cottini MD, Giordano Zampi MD, Amedeo Pergolini MD, Vincenzo Polizzi MD, Francesco Musumeci MD, FECTS. "Double Orifice Fissured Subaortic Membrane in the Adult" International Journal of Cardiovascular Practice, Jan 2017, Volume 2, Issue 1 (24-26). DOI: 10.21859/ijcp-020107.
26. Marco Picichè, Federico Ranocchi, Brenno Fiorani, Marcello Bergonzini, Mariano Feccia,
Andrea Montalto, Cesare D' Alessandro, Marzia Cottini, Riccardo Gherli, Bruno Mariani,
Gabriella Parisi, Giovanni Casali, Gianpaolo Luzi, Amedeo Pergolini, Emilio Ferretti, Fiorella Giacopino, Saverio Leonardi Cattolica, Lino Madaro and Francesco Musumeci. Surgical treatment of Valvular Infective Endocarditis Complicated by An Abscess: A Single Center’s Experience. Interv Cardiol J 2017, 3:1;
27. Angela Lappa MD, Marzia Cottini MD, Patrizia Picozzi MD, Silvia Donfrancesco MD, Davino Emilio MD, Valentina Coltelli MD, Di Pirro Lucio MD, , Luca Severi MD, Francesco Musumeci Prof, High Thoracic Epidural Anaesthesia for Endocardial Ablation of Atrial Fibrillation: A Single Centre Experience ARC Journal of Anesthesiology, Volume 2, Issue 1, 2017, PP 7-11 , ISSN No. (Online) 2455-9792. DOI: http://dx.doi.org/10.20431/2455-9792.0201003. www.arcjournals.org
28. Agnese Ricotta, Marzia Cottini, Paola Lilla Della Monica, Fabio Sbaraglia Vincenzo Polizzi, Giada Di Stefano, Amedeo Pergolini, Angela Lappa, Silvia Donfrancesco, Angela Lappa, Francesco Musumeci. PERIPARTUM CARDIOMYOPATHY. FOUR CASE REPORTS WITH DIFFERENT OUTCOMES. Cardiovascular Therapy 2017, 2:2.
29. Cottini M, Pergolini A, Ranocchi F, Musumeci F . The role of heart team approach in penetrating cardiac trauma: case report and review of the literature. Brazilian Journal of Cardiovascular Surgery, 2018, Volume 33 (1), DOI: http://dx.doi.org/10.21470/1678-9741-2017-0150.
30. Zampi G, Pergolini A, Pontillo D, Cottini M. Abdominal ascitic fluid: tricky concealing of the electrocardiogram. Kardiol Pol. 2017; 75(8): 814. doi: 10.5603/KP.2017.0157.
31. Angela Lappa , Marzia Cottini, Silvia Donfrancesco, Mariano Feccia, Amedeo Pergolini, Vincenzo Polizzi, Fabio Sbaraglia, Giada Distefano, Paola Lilla della Monica, Grillo Lucia Rosalba , Francesco Musumeci. Primary cardiac kaposiform hemangioendothelioma: the rare adult-onset. Review of the literature. EC anesthesia, 3 (1): 04-17.
32. Marzia Cottini, The revolution of cardiac surgery evolution. Letter to Editor. Archives of Surgery and Clinical Research, Heighten Science Publications Corporations, Arch Surg Clin Res 2017; 1: 049-050
33. Marzia Cottini, Angela Lappa, Silvia Donfrancesco. Primary cardiac hemangioendothelioma in the adult and cardiac involvement in patient with non-cardiac hemangioendothelioma. Cancer Studies and Therapeutics (ISSN: 2002-7184), Cancer Stud Ther J, Volume 2(5): 1-6, 2017
34. Marzia Cottini, A. Lappa, S. Donfrancesco, Francesco Musumeci. Evolution of anaesthesia in transapical aortic valve implantation. International Journal of Clinical Anesthesia and Research. Int J Clin Anesth Res 2017; 1: 020-023.
35. Zampi G, Pergolini A, Ponillo D, Cottini M. Abdominal Ascitis fluid: tricky concealing of the electrocardiogram. Polska Heart Journal, Kardiol Pol. 2017;758): 814. doi: 10.5603/KP.2017.0157.
36. Federico Ranocchi, Marco Picichè, Marzia Cottini, Emilio Ferretti and Francesco Musumeci. Inferior ischemic ventricular septal defect: atypical triple pericardial patch implantation technique.Interventional Cardiology (2017), 9(6), 239-242.
37. Marzia Cottini. ECMO and emergency medicine: future perspectives. J Emerg Med Forecast 2018; 1(1); 1001.
38. Buffa V, Cottini M, Madau M, et al. Thrombosis of giant right coronary aneurysm: A 3-D reconstruction. Surg Case Rep 2017;1(1):11.
39. Alessandro Costetti, Marco Lanfranconi, Marzia Cottini, Maria Pia Gagliardone, Claudio Francesco Russo. Cardiac Surgery in Jehovah's Witnesses: Another Frontier Overcoming. ARC Journal of Cardiology Volume 4, Issue 1, 2018, PP 1-2 ISSN No. (Online) 2455-5991 DOI: http://dx.doi.org/10.20431/2455-5991.040100

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