Jonas G. Croissant, PhD

Research Assistant Professor

Chemical & Biological Engineering

University of New Mexico (UNM)

Albuquerque, NM 87131, USA


Biography

EDUCATION
• Ph.D. Chemical Engineering National School of Chemistry Montpellier 2014
GPA Equivalent 4.0/4.0 Montpellier, France
• M.S. Chemical Engineering University of Montpellier 2011
GPA Equivalent 4.0/4.0 Montpellier, France
• B.S. Chemistry University of Montpellier 2009
Montpellier, France

Research Interest

• Sol-gel design of porous and non-porous organosilica nanomaterials: mesoporous silica, periodic mesoporous organosilica, bridged silsesquioxane NPs, and colloidosomes.
• Biodegradable nanomaterials.
• Nanomedicine: imaging, drug delivery, photothermal and photodynamic therapies.
• Two-photon-sensitive nanotheranostic elaboration.

Scientific Activities

AWARDS & HONORS
• Materials Horizons Outstanding Reviewer, Royal Society of Chemistry, 2017
Top 10 reviewers for the journal (IF:10.7) in the world based on the number, timeliness and quality of the reports.
• Ph.D. Thesis Prize Languedoc-Roussillon French Society of Chemistry, 2015
• Ph.D. Thesis Prize TOTAL©/Balard Chemistry Foundation, 2015
Best Ph.D. thesis in Chemistry (all disciples included) among various southern universities (~200 students).
• First Prize of Oral Presentation French Society of Chemistry, 2013
1st Young Researcher's Mediterranean Workshop, Montpellier, France.
• Mobility and Excellency Scholarship Balard Chemistry Foundation, 2011
• Mobility and Excellency Scholarship University of Montpellier, 2011
• Merit Scholarships French Government 2009, 2010, 2011
Top of the year in B.S. and M.S. (1st rank over 30 students). Best Master Thesis

Publications

PEER-REVIEWED PUBLICATIONS (†Equal contribution)
Overview in numbers: 37 peer-reviewed publications in international journals including 21 first-author articles, 8 corresponding author articles, 5 review articles, and two invited book chapters. Research career: 2011-2018; h-index 20; 1100+ citations (Google Scholar).
37. B. T. Vu, S. A. Shahin, J. G. Croissant, Y. Fatieviev, K. Matsumoto, T. L. Hoang Doan, T. Yik, A. Conteras, L. Ratliff, C. Mauriello Jimenez, L. Raehm, N. M. Khashab, J-O. Durand, C. Glackin and F. Tamanoi,* “Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer,” Sci. Rep., 2018, just accepted. Article level metrics = 105 (12 online news outlets), top 3 % of 137,257 tracked articles of a similar age in all journals.
36. C. Mauriello-Jimenez,† D. Aggad,† J. G. Croissant, K. Tresfield, D. Laurencin, D. Berthomieu, N. Cubedo, M. Rossel, S. Alsaiari, D. H. Anjum, R. Sougrat, M. A. Roldan-Gutierrez, S. Richeter, E. Oliviero, L. Raehm, C. Charnay, X. Cattoën, S. Clément, M. Wong Chi Man, M. Maynadier, V. Chaleix, V. Sol, M. Garcia, M. Gary-Bobo, N. M. Khashab, N. Bettache,* J-O. Durand,* “Porous Porphyrin-Based Organosilica Nanoparticles for NIR Two-Photon Photodynamic Therapy and Gene Delivery in Zebrafish,” Adv. Funct. Mater., 2018, 1800235. Selected for a Frontpiece Cover.
35. Y. Fu, Y-B. Jiang,* D. Dunphy, H. Xiong, E. Coker, S. Chou, H. Zhang, J. M. Vanegas, J. G. Croissant, J. L. Cecchi, S. B Rempe, C. J. Brinker, “Ultra-thin enzymatic liquid membrane for CO2 separation and capture,” Nat. Comm., 2018, 9, 990. Article level metrics = 83 (9 online news outlets), top 4 % of 204,379 articles tracked. Highlighted in Nature Energy.
34. J. G. Croissant,* J. I. Zink, L. Raehm, J-O. Durand, “Two-Photon-Excited Silica and Organosilica Nanoparticles for Spatiotemporal Cancer Treatment,” Adv. Health. Mater., 2018, just accepted. Press Release from the French National Center for Scientific Research. Selected in Wiley Hot Topics 03/18. Selected for the journal Back Cover.
33. J. G. Croissant, Y. Fatieiev, A. Almalik, N. M. Khashab,* “Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications,” Adv. Health. Mater., 2018, adhm.201700831. Selected in Wiley Hot Topics 12/17. 2nd Most read and downloaded article in March 2018.
32. D. Aggad, C. Mauriello Jimenez, S. Dib, J. G. Croissant, L. Lichon, D. Laurencin, S. Richeter, M. Maynadier, S. K. Alsaiari, M. Boufatit, L. Raehm, M. Garcia, N. M. Khashab, M. Gary-Bobo,* J-O. Durand,* “Gemcitabine Delivery and Photodynamic Therapy in Cancer Cells via Porphyrin-Ethylene-Based Periodic Mesoporous Organosilica Nanoparticles,” ChemNanoMat, 2018, 4, 46.
31. K. Alamoudi, P. Martins, J. G. Croissant, S. Patil, H. Omar, N. M. Khashab,* “Thermo-Responsive Pegylated Bubble Liposome Nanovectors for Efficient siRNA Delivery via Endosomal Escape,” Nanomedicine., 2017, 12, 1421.
30. S. Alsaiari, M. Amen Hammami, J. G. Croissant, H. W. Omar, P. Neelakanda, T. Yapici, K.-V. Peinemann, N. M. Khashab,* “Colloidal Gold Nanoclusters Spiked Silica Fillers in Mixed Matrix Coatings: Simultaneous Detection and Inhibition of Healthcare-Associated Infections,” Adv. Health. Mater., 2017, 6, 1601135. Selected as Inside Front Cover. Article level metrics = 27 (3 online news outlets), top 5 % of 8.2 million articles tracked by Altmetric.
29. Y. Fatieiev, J. G. Croissant, K. Alamoudi, N. M. Khashab,* “Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: from Nanospheres to Nanowires,” ChemPlusChem, 2017, 9, 1737. Selected in Wiley Hot Topics 02/17.
28. J. G. Croissant, Y. Fatieiev, N. M. Khashab,* “Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles,” Adv. Mater., 2017, 29, 1604634. Selected as Front Cover. 65 citations (Google Scholar).
27. M. Amen Hammami, J. G. Croissant, L. Francis, N. Ghaffour, S. Alsaiari, N. M. Khashab,* “Engineering Hydrophobic Organosilica Doped Nanofibers for Enhanced and Fouling Resistant Membrane Distillation,” ACS Appl. Mater. Interfaces, 2017, 9, 1737.
26. J. G. Croissant,* X. Cattoën, J-O. Durand, M. Wong Chi Man, N. M. Khashab,* “Organosilica Hybrid Nanomaterials with a High Organic Content: Syntheses and Applications of Silsesquioxanes,” Nanoscale, 2016, 8, 19945.

25. H. Omar, J. G. Croissant, L. Deng, K. Alamoudi, S. Alsaiari, R. Laamarti, D. H. Anjum, P. Martins, B. Moosa, N. M. Khashab,* “Biodegradable Magnetic Silica@Iron Oxide Nanovectors with Ultra-Large Mesopores for High Protein Loading, Magnetothermal Release, and Delivery,” J. Control. Rel., 2016, 8, 19945. Selected for an Audioslide.
24. C. Mauriello-Jimenez, Y. Galàn Rubio, N. Knezevic, S. Szunerits, K. Manakamana, O. Hocine, J. G. Croissant, M. Seric, L. Raehm, V. Stojanovic, M. Maynadier, M. Garcia, M. Gary-Bobo,* J-O. Durand,* “Nanodiamond–PMO for Two-Photon PDT and Drug Delivery,” J. Mater. Chem. B, 2016, 4, 5803.
23. J. G. Croissant,† S. Picard,† M. Maynadier, O. Mongin, V. Hugues, C. Mauriello, M. Klausen, E. Genin, X. Cattoën, M. Wong Chi Man, L. Raehm, M. Garcia, M. Gary-Bobo,* M. Blanchard-Desce,* J-O. Durand,* “Fluorescent Periodic Mesoporous Organosilica Nanoparticles Dual-Functionalized via Click Chemistry for Two-Photon Photodynamic Therapy in Cells,” J. Mater. Chem. B, 2016, 4, 5567.
22. J. G. Croissant, Y. Fatieiev, K. Julfakyan, J. Lu, A-H. Emwas, D. H. Anjum, H. Omar, F. Tamanoi, J. I. Zink, N. M. Khashab,* “Biodegradable Oxamide-Phenylene-Based Mesoporous Organosilica Nanoparticles with Unprecedented Drug Payloads for Delivery in Cells,” Chem. Eur. J., 2016, 22, 14806. Selected as Frontpiece. Highlighted in atlasofscience.org.
21. J. G. Croissant, Y. Fatieiev, H. Omar, D. H. Anjum, A. Gurinov, J. Lu, F. Tamanoi, J. I. Zink,* N. M. Khashab,* “Periodic Mesoporous Organosilica Nanoparticles with Controlled Morphologies and High Drug/Dye Loadings for Multi-Cargo Delivery in Cancer Cells,” Chem. Eur. J., 2016, 22, 9607.
20. J. G. Croissant, D. Zhang, J. Lu, L. Deng, A. Mashat, L. Hu, F. Tamanoi, J. I. Zink, N. M. Khashab,* “Protein-Gold Clusters-Capped Mesoporous Silica Nanoparticles for High Drug Loading, Autonomous Gemcitabine/Doxorubicin Co-Delivery, and In-Vivo Tumor Imaging,” J. Control. Rel., 2016, 229, 183. Highlighted in Nature Middle East.
19. J. G. Croissant,* C. Qi, M. Maynadier, X. Cattoën, M. Wong Chi Man, L. Raehm, O. Mongin, M. Blanchard-Desce, M. Garcia, M. Gary-Bobo,* J-O. Durand,* “Multifunctional Gold-Mesoporous Silica Nanocomposites for Enhanced Two-Photon Imaging and Therapy of Cancer Cells,” Front. Mol. Biosci., 2016, 3, 1.
18. J. G. Croissant,* X. Cattoën, M. Wong Chi Man, J-O. Durand,* N. M. Khashab,* “Synthesis and Applications of Periodic Mesoporous Organosilica Nanoparticles,” Nanoscale, 2015, 7, 20318. 70 citations (Google Scholar).
17. Y. Fatieiev,† J. G. Croissant,† S. Alsaiari, B. A. Moosa, N. M. Khashab,* “Bridged Silsesquioxane Nanoparticles with Tunable Morphologies for Light-Triggered DNA Delivery,” ACS Appl. Mater. Interfaces, 2015, 7, 24993. Selected as Front Cover.
16. Y. Fatieiev, J. G. Croissant, K. Julfakyan, L. Deng, D. H. Anjum, N. M. Khashab,* “Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging,” Nanoscale, 2015, 7, 15007. Selected as Front Cover.
15. J. Croissant, C. Qi, O. Mongin,* V. Hugues, M. Blanchard-Desce, L. Raehm, X. Cattoën, M. Wong Chi Man, M. Maynadier, M. Garcia, M. Gary-Bobo, J. I. Zink,* J-O. Durand,* “Disulfide-Gated Mesoporous Silica Nanoparticles Designed for Two-Photon-Triggered Drug Release and Imaging,” J. Mater. Chem. B, 2015, 3, 6456.
14. J. Croissant,† C. Mauriello-Jimenez,† X. Cattoën, M. Wong Chi Man, L. Raehm, M. Maynadier, M. Gary-Bobo, M. Garcia, P. Maillard, J-O. Durand,* “Synthesis of Disulfide-Based Biodegradable
Bridged Silsesquioxane Nanoparticles for Two-Photon Imaging and Therapy of Cancer Cells,” Chem. Commun., 2015, 51, 12324.
13. J. Croissant,* O. Mongin,* V. Hugues, M. Blanchard-Desce, X. Cattoën, M. Wong Chi Man, M. Maynadier, M. Garcia, M. Gary-Bobo, L. Raehm, J-O. Durand,* “Influence of the Synthetic Method on the Properties of Two-Photon-Sensitive Mesoporous Silica Nanoparticles,” J. Mater. Chem. B, 2015, 3, 5182.
12. C. Mauriello-Jimenez, J. Croissant, M. Maynadier, X. Cattoën, M. Wong Chi Man, J. Vergnaud, V. Chaleixb, V. Sol, M. Garcia, M. Gary-Bobo, L. Raehm, J-O. Durand,* “Porphyrin-Functionalized Mesoporous Organosilica Nanoparticles for Two-Photon Imaging of Cancer Cells and Drug Delivery,” J. Mater. Chem. B, 2015, 3, 3681.
11. S. Li, B. A. Moosa, J. G. Croissant, N. M. Khashab,* “Electrostatic Assembly/ Disassembly of Nanoscaled Colloidosomes for Light-Triggered Cargo Release,” Angew. Chem. Int. Ed., 2015, 127, 6908. Selected as “Hot Paper,” Inside Back Cover. Highlighted in Nature Middle East.
10. J. Croissant,* X. Cattoën,* M. Wong Chi Man, P. Dieudonné, C. Charnay, L. Raehm, J-O. Durand,* “One-Pot Construction of Multipodal Hybrid Periodic Mesoporous Organosilica Nanoparticles with Crystal-Like Architectures,” Adv. Mater., 2015, 27, 145.
9. J. Croissant, M. Maynadier, O. Mongin, V. Hugues, M. Blanchard-Desce, X. Cattoën, M. Wong Chi Man, A. Gallud, M. Gary-Bobo, M. Garcia, L. Raehm, J-O. Durand,* “Enhanced Two-Photon Fluorescence Imaging and Photodynamic Therapy of Cancer Cells via Gold@Bridged Silsesquioxane Nanoparticles,” Small, 2015, 11, 295.
8. J. Croissant,* X. Cattoën, M. Wong Chi Man, A. Gallud, L. Raehm, M. Maynadier,* J-O. Durand,* “Biodegradable Ethylene-bis(propyl)Disulfide-Based Periodic Mesoporous Organosilica Nanorods and Nanospheres for Efficient In-Vitro Drug Delivery,” Adv. Mater., 2014, 26, 6174. 97 citations (Google Scholar).
7. J. Croissant, D. Salles, M. Maynadier, O. Mongin, V. Hugues, M. Blanchard-Desce,* X. Cattoën, M. Wong Chi Man, A. Gallud, M. Garcia, M. Gary-Bobo,* L. Raehm, J-O. Durand,* “Mixed Periodic Mesoporous Organosilica Nanoparticles and Core-Shell Systems, Application to In-Vitro Two-Photon Imaging, Therapy and Drug Delivery,” Chem. Mater., 2014, 26, 7214.
6. S. Dib, M. Boufatit, S. Chelouaou, F. Sadi-Hassaine, J. Croissant,* J. Long, L. Raehm, C. Charnay, J-O. Durand, “Versatile Heavy Metals Removal via Magnetic Mesoporous Nanocontainers,” RSC Adv., 2014, 4, 24838.
5. J. Croissant, A. Chaix, O. Mongin, M. Wang, S. Clément, L. Raehm, J-O. Durand,* V. Hugues, M. Blanchard-Desce, M. Maynadier, A. Gallud, M. Gary-Bobo,* M. Garcia, J. Lu, F. Tamanoi, D. P. Ferris, D. Tarn, J. I. Zink,* “Two-Photon-Triggered Drug Delivery via Fluorescent Nanovalves,” Small, 2014, 10, 1752. Article level metrics = 108 (13 online news outlets), higher than 99% of its peers in the journal Small, top 5 % of 6.6 million articles tracked by Altmetric. 65 citations (Google Scholar).
4. X. Cattoën,* A. Noureddine, J. Croissant, N. Moitra, K. Bürglová, J. Hodačová, O. De Los Cobos, M. Lejeune, F. Rossignol, D. Toulemon, S. Bégin-Colin, B. P. Pichon, L. Raehm, J-O. Durand, M. Wong Chi Man, “Click Approaches in Sol-Gel Chemistry,” J. Sol-Gel Sci. Technol., 2014, 70, 245.
3. J. Croissant, M. Maynadier, A. Gallud, H. P. N'Dongo, J. L. Nyalosaso, G. Derrien, C. Charnay, J-O. Durand,* L. Raehm, F. Serein-Spirau, N. Cheminet, T. Jarrosson, O. Mongin, M. Blanchard-Desce, M. Gary-Bobo,* M. Garcia, J. Lu, F. Tamanoi, D. Tarn, T. M. Guardado-Alvarez, J. I. Zink,* “Two-Photon-Triggered Drug Delivery in Cancer Cells via Nanoimpellers,” Angew. Chem. Int. Ed., 2013, 125, 14058. 71 citations (Google Scholar).

2. J. Croissant, J. I. Zink,* “Nanovalve-Controlled Cargo Release Activated by Plasmonic Heating,” J. Am. Chem. Soc., 2012, 134, 7628. 162 citations (Google Scholar).
1. M. Reinholdt, J. Croissant, L. Di Carlo, D. Granier, P. Gaveau, S. Bégu, J-M. Devoisselle, P. H. Mutin, M. E. Smith, C. Bonhomme, C. Gervais, A. van der Lee, D. Laurencin,* “Synthesis and Characterization of Crystalline Structures Based on Phenylboronate Ligands Bound to Alkaline Earth Cations,” Inorg. Chem., 2011, 50, 7802.
PUBLICATIONS IN PROGRESS
10 P. Dogra, N. L. Adolphi, Y-S. Lin, K. S. Butler, P. N. Durfee, J. G. Croissant, A. Noureddine, E. N. Coker, E. L. Bearer, Z. Wang, V. Cristini,* C. J. Brinker,* “Establishing the effects of physicochemical properties and routes of administration on in vivo nanoparticle disposition,” 2018, submitted to Nature Nanotechnology, sent back after the reviewer’s report.
9. A. Nourredine, E. Hjelvik, J. G. Croissant, P. N. Durfee, J. Agola, C. J. Brinker,* “Engineering of Large-Pore Lipid-Coated Mesoporous Silica Nanoparticles for Dual Cargo Delivery to Cancer Cells,” 2018, submitted.
8. J. G. Croissant, K. Butler, J. I. Zink, C. J. Brinker,* “Synthetic Amorphous Silica Nanoparticles: Toxicity and Biomedical and Environmental Implications,” 2018, invited review for Nature Materials Review, to be submitted.
7. J. O. Agola*, D. Dunphy, M. Salazar, S. Jett, C. Theron, S. Pokhrel, L. Mädler, A. Prossnitz, J. G. Croissant, P. Durfee, T. McGregor, P. A. Holden, R. Li, A. Nel, C. J. Brinker,* “Rare Earth Phosphate Nanocrystal Modification of Bacteria via Solubility-Driven Dephosphorylation Pathways Promotes Biofilm Formations” 2018, to be submitted.
6. W. Zhu, J. Guo, J. G. Croissant, S. Amini, J. O. Agola, Y. Ju, J. Shang, A. Noureddine, F. Caruso, S. Wuttke, C. J. Brinker,* “SupraCells: Living Mammalian Cells Coated with Functional Modular Nanoparticle-Based Exoskeletons,” 2018, to be submitted.
5. W. Zhu, J. Guo, J. G. Croissant, S. Amini, J. O. Agola, Y. Ju, S. D. Jett, S. Wuttke, F. Caruso, C. J. Brinker,* “Supracells: Living Cells Coated with Nanoparticle-Based Exoskeletons,” 2018, to be submitted.
4. J. G. Croissant, Y. Zhang, Y. Fatieiev, P. Hoang, L. Deng, D. H. Anjum, N. M. Khashab,* “Gold Core Mesoporous Organosilica Shell Nanoparticles and Pickering Emulsions,” 2018, to be submitted.
3. J. G. Croissant, J. I. Zink,* “Controllable Photodegradation of Mesoporous Silica Encapsulating Gold Cores for Remote Cargo Release,” 2018, to be submitted.
2. J. G. Croissant, M. Maynadier,* M. Blanchard-Desce, A. Delalande et al. “Two-Photon-Triggered Gene Silencing in Cells with Azobenzene-Mesoporous Silica Nanoparticles,” 2018, to be submitted.
1. C. Mauriello-Jimenez, J. G. Croissant, V. Stojanovič, M. Maynadier, M. Gary-Bobo, M. Garcia, M. Blanchard-Desce, O. Mongin, L. Raehm, J-O. Durand, M. Cohen, F. Delie,* “Two-Photon Photosensitizers encapsulation in PLA Nanoparticles,” 2018, to be submitted.

Join as a Editor