Michalis Katsimpoulas, DVM, PhD , SRS

Research Staff Scientist-Assistant Professor Level

Experimental Surgery Unit

Center of Clinical, Experimental Surgery and Translational Research

Βιοmedical Research Foundation of the Academy of Athens

4, Soranou Ephesius str., 11527, Athens, Greece


Biography

Education
2008-2013, PhD from the Medical School of Athens (Vascular Surgery Department)
1996-2002 ,D.V.M. Veterinary Faculty, Aristotle University of Thessaloniki, Greece.
1988-1994, Molaoi High School, Lakonia, Greece.

Research Interest

Scientific Activities

Awards
1. 22nd European Tissue Repair Society (ETRS) Annual Meeting, Athens, Greece, 4-5/10/12. Poster presentation: Vascular endothelium, shear stress and polycystins 1 and 2: Data from rabbits and humans. Varela A, Katsimpoulas M, Agrogiannis E, Sigala F, Davos C, Piperi C, Papavasiliou A, Basdra E. (Young Investigator Award)
2. 9th International Symposium on Modern Concepts in Endocarditis and Cardiovascular Infections, Heidelberg, Germany, 14-17/06/07. Oral presentation: Intermittent vs continuous infusion of vancomycin in rabbit model of experimental endocarditis due to E. faecium: preliminary results. Vryonis E, Perivolioti E, Fanourgiakis P, Mylona E, Mantziaras G, Katsimpoulas M, Samarkos M, Kostomitsopoulos N, Karayannacos PE, Paniara O, Skoutelis A. (Certificate of Achievement)

Memberships
- Hellenic Veterinary Medical Society
- Hellenic Society of Veterinary Orthopedics and Traumatology
- Hellenic Veterinary Association
- Geotechnical Chamber of Greece
- European Society for Surgical Research
- Academy of Surgical Research
- American Veterinary Medical Association
- European Society of Vascular Surgeons

Publications

Publications in International scientific journals
1. Bakopoulos A, Kapelouzou A, Tsilimigras DI, Katsimpoulas M, Schizas D, Aravanis C, Balafas E, Mavroidis M, Pavlakis K, Machairas A, Liakakos T. Expression of Toll-like receptors (TLRs) in the lungs of an experimental sepsis mouse model.PLoS One. 2017 Nov 14;12(11). .PMID: 29136027
2. Tzimas C, Johnson DM, Santiago DJ, Vafiadaki E, Arvanitis DA, Davos CH, Varela A, Athanasiadis NC, Dimitriou C, Katsimpoulas M, Sonntag S, Kryzhanovska M, Shmerling D, Lehnart SE, Sipido KR, Kranias EG, Sanoudou D. Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.Cardiovasc Res. 2017 Sep 1;113(11):1403-1417. PMID: 28859293
3. Varela A, Mavroidis M, Katsimpoulas M, Sfiroera I, Kappa N(2), Mesa A(1), Kostomitsopoulos NG(1), Cokkinos DV(1).The neuroprotective agent Rasagiline mesylate attenuates cardiac remodeling after experimental myocardial infarction.ESC Heart Fail. 2017 Aug;4(3):331-340. PMID: 28772050
4. Kapelouzou A, Giaglis S, Peroulis M, Katsimpoulas M, Moustardas P, Aravanis CV, Kostakis A, Karayannakos PE, Cokkinos DV.Overexpression of Toll-Like Receptors 2, 3, 4, and 8 is Correlated to the Vascular Atherosclerotic Process in the Hyperlipidemic Rabbit Model: The Effect of Statin Treatment.J Vasc Res. 2017 May 5;54(3):156-169. PMID: 28478461
5. Katsimpoulas M, Kadoglou NE, Moustardas P, Kapelouzou A, Dede E, Kostomitsopoulos N, Karayannacos PE, Kostakis A, Liapis CD. The role of exercise training and the endocannabinoid system in atherosclerotic plaque burden and composition in Apo-E-deficient mice. Hellenic J Cardiol. 2016 Nov 16. PMID: 28254386
6. Kouroupis D, Kyrkou A, Triantafyllidi E, Katsimpoulas M, ChalepakisG, Goussia A, Georgoulis A, Murphy C, Fotsis T.Generation of stem cell-based bioartificial anterior cruciate ligament (ACL) grafts for effective ACL rupture repair.Stem Cell Res. 2016 Sep;17(2):448-457. PMID: 27217303
7. Athanasiadis D, Kapelouzou A, Martikos G, Katsimpoulas M, Schizas D, Vasdekis SN, Kostakis A, Liakakos TD, Lazaris AM.Remote Ischemic Preconditioning May Attenuate Renal Ischemia-Reperfusion Injury in a Porcine Model of Supraceliac Aortic Cross-Clamping.J Vasc Res. 2015;52(3):161-71. PMID: 26745363
8. Ntourakis D, Katsimpoulas M, Tanoglidi A, Barbatis C, Karayannacos PE, Sergentanis TN, Kostomitsopoulos N, Machairas A. Adhesions and Healing of Intestinal Anastomoses: The Effect of Anti-Adhesion Barriers. Surg Innov. 2015 Oct 15. PMID: 26474604
9. Katsimpoulas M, Morticelli L, Michalopoulos E, Gontika I, Stavropoulos-Giokas C, Kostakis A, Haverich A, Korossis S.Investigation of the biomechanical integrity of decellularized rat abdominal aorta. Transplant Proc. 2015 May;47(4):1228-33. PMID: 26036560
10. Moustardas P, Kadoglou NP, Katsimpoulas M, Kapelouzou A, Kostomitsopoulos N, Karayannacos PE, Kostakis A, Liapis CD. The Complementary Effects of Atorvastatin and Exercise Treatment on the Composition and Stability of the Atherosclerotic Plaques in ApoE Knockout Mice. PLoS One. 2014 Sep 29;9 (9). PMID: 25264981
11. Zacharoulis D, Rountas C, Katsimpoulas M, Morianos J, Chatziandreou I, Vassilopoulos G. Efficient liver gene transfer with foamy virus vectors. Med Sci Monit Basic Res. 2013 Aug 14;19:214-20. PMID: 23941977
12. Karagianni F, Prakoura N, Kaltsa G, Politis P, Arvaniti E, Kaltezioti V, Psarras S, Pagakis S, Katsimpoulas M, Abed A, Chatziantoniou C, Charonis A. Transgelin Up-Regulation in Obstructive Nephropathy. PLoS One. 2013 Jun 26;8(6). PMID: 23840546
13. Kadoglou NP, Moustardas P, Kapelouzou A, Katsimpoulas M, Giagini A, Dede E, Kostomitsopoulos N, Karayannacos PE, Kostakis A, Liapis CD. The anti-inflammatory effects of exercise training promote atherosclerotic plaque stabilization in apolipoprotein E knockout mice with diabetic atherosclerosis. Eur J Histochem. 2013 Mar 25;57(1). PMID: 23549462
14. Kadoglou NP, Moustardas P, Katsimpoulas M, Kapelouzou A, Kostomitsopoulos N, Schafer K, Kostakis A, Liapis CD. The Beneficial Effects of a Direct Thrombin Inhibitor, Dabigatran Etexilate, on the Development and Stability of Atherosclerotic Lesions in Apolipoprotein E-deficient Mice: Dabigatran etexilate and atherosclerosis. Cardiovasc Drugs Ther. 2012 Oct;26(5):367-74. PMID:22940777
15. Kanakis MA, Katsimpoulas M, Kavantzas N, Kostomitsopoulos N, Dimitriou C, Lioulias A, Kostakis A, Mitropoulos F. Acute histological changes of the lung after experimental Fontan circulation in a swine model. Med Sci Monit. 2012 Sep;18(9):BR362-5. PMID: 22936186
16. Zacharoulis D, Lazoura O, Rountas C, Katsimpoulas M, Zachari E, Angelini GD, Habib NA.A new endovascular radiofrequency device for dilatation of vascular stenosis in a rabbit model. J Invest Surg. 2012 Aug;25(4):253-61.PMID: 22571174
17. Lampropoulos KM, Sokolis DP, Dimitriou CA, Katsimpoulas M, Balafas E, Agapaki A, Karayannacos PE, Boudoulas H. The effect of propranolol on aortic structure and function in normotensive rats. Hellenic J Cardiol. 2012 Mar;53(2):101-7.PMID: 22484775
18. Fanourgiakis PS, Kraniotaki EP, Platsouka ED, Perivolioti EP, Katsimpoulas M, Gikas EE, Tsarbopoulos AC, Paniara OI, Skoutelis AT. Real-time polymerase chain reaction seems not to be superior to blood cultures in anticipating valve sterilization in infective endocarditis. Hellenic J Cardiol. 2011 Nov-Dec;52(6):555-6. PMID: 22143022
19. Varela A, Katsimpoulas M, Tousoulis D, Politi K, Papaioannou TG, Vaina S, Davos CH, Piperi C, Stefanadis C, Basdra EK, Papavassiliou AG.Early shear stress signaling on vascular endothelium by a modified partial carotid ligation model. Int J Cardiol. 2011 Nov 3;152(3):413-6. PMID: 21917331 (equally contributed)
20. Agathos EA, Shen M, Katsiboulas M, Koutsoukos P, Gloustianou G. In vivo calcification of glutaraldehyde-fixed cardiac valve and pericardium of Phoca groenlandica. ASAIO J. 2011 Jul-Aug;57(4):328-32. PMID: 21502861
21. Zacharoulis D, Lazoura O, Rountas C, Katsimpoulas M, Mantzianas G, Tzovaras G, Habib N. Experimental animal study of a novel radiofrequency endovascular occlusion device. Am J Surg. 2011 Jul;202(1):103-9. PMID: 21741521
22. Balafas E, Papastefanou A, Katsimpoulas M, Kostomitsopoulos N. A Low Cost Face Mask for Inhalation Anaesthesia in Rats. Scand. J. Lab. Anim. Sci. 2011 Vol. 38 No. 2
23. Lazoura O, Zacharoulis D, Kanavou T, Rountas C, Katsimboulas M, Tzovaras G, HabibN. A novel experimental animal model of arterial stenosis based on endovascular radiofrequency energy application. J Invest Surg. 2011;24(3):123-8. PMID: 21524178
24. Kadoglou NP, Kostomitsopoulos N, Kapelouzou A, Moustardas P, Katsimpoulas M, Giagini A, Dede E, Boudoulas H, Konstantinides S, Karayannacos PE, Liapis CD. Effects of exercise training on the severity and composition of atherosclerotic plaque in apoE-deficient mice. J Vasc Res. 2011;48(4):347-56. PMID:21389732
25. Katsimpoulas M, Zacharoulis D, Rountas C, Dimitriou C, Mantziaras G, Kostomitsopoulos N, Habib N, Kostakis A. Minimal invasive technique for gene delivery in porcine liver lobe segment. J Invest Surg. 2011;24(1):13-7. PMID: 21275525
26. Kanakis MA, Mitropoulos FA, Katsimpoulas M, Dimitriou C, Peroulis M,Kostomitsopoulos N, Lioulias A, Kostakis A. Experimental modified Fontan circulation in a swine model without the use of cardiopulmonary bypass. Med Sci Monit 2011 Jan;17(1) PMID: 21169902


Publications in peer review Greek scientific journals
1. Katsimpoulas M, Foteinou M, Paronis E, Alexakos P, Kostomitsopoulos N. Pituitary adenoma in aged rats. A case report. JHVMS 2008; 59(1):58-63
2. Katsimpoulas M, Kakisis I, Peroulis M, Dimitriou K, Balafas E, Kostomitsopoulos N. Fatal venous air embolism in swine during surgical procedure. JHVMS 2008; 59(1):71-76

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