Shih-Feng Chou, PhD

Assistant Professor

Department of Mechanical Engineering

The University of Texas at Tyler



Dr. Shih-Feng Chou received a Bachelor of Science degree in Mechanical Engineering at National Chiao Tung University (Hsinchu City, Taiwan) in 2001. He was a graduate research and teaching assistant from 2003 to 2006 in the Department of Mechanical Engineering and Energy Processes at Southern Illinois University Carbondale (Carbondale IL.) when he received his Master of Science degree in 2005. He received his Doctor of Philosophy degree in Materials Engineering at Auburn University (Auburn AL.) in 2011. He then worked as a research associate at Thayer School of Engineering at Dartmouth College (Hanover NH.) from 2012 to 2013. He later worked as a senior fellow in the Department of Bioengineering at University of Washington (Seattle WA.) from 2014 to 2016.

He joined the Department of Mechanical Engineering at The University of Texas at Tyler as an assistant professor in September 2016.
Dr. Chou has many years of research experience in structure-property relationship of biomaterials. He is interested in several advanced manufacturing techniques for the fabrication of functional biomaterials with outstanding mechanical properties using natural and/or synthetic polymers. Dr. Chou’s research focuses on addressing current challenges in drug delivery and tissue engineering using these multi-functional biomaterials. He has authored/coauthored in 24 Journal articles and 4 Conference Proceedings in the field of mechanical properties, drug release, and cell culture using biomaterials. A complete and updated publication record from Dr. Chou can be found at

Research Interest

- Biomaterials
- Structure property relationships of materials
- Drug release
- Tissue engineering

Scientific Activities


1. M. Small, A. Faglie, A.J. Craig, M. Pieper, V.E. Fernand, P.F. Nueunschwander, S.F. Chou, Nanostructure-enabled and nanotextured 2D surfaces for biomedical applications, Micromachines, April (2018), Submitted.
2. Y.Y. Hsu, C.Y. Liu, S.F. Chou, S.Y. Lee, Sleep, fatigue, and depressive symptoms among gynecological cancer postsurgical treatment patients in Taiwan, European Journal of Oncology Nursing, April (2018) Submitted.
3. M.A. Gizaw, J. Thompson, A. Faglie, S.Y. Lee, P. Neuenschwander, S.F. Chou, The use of electrospun nanofibers as a dressing material for delivery of drugs and biological agents in wound healing, Bioengineering, 5 (2018) 9. doi:10.3390/bioengineering5010009
4. L.J. Luo, J.Y. Lai, S.F. Chou, Y.J. Hsueh, D.H.K. Ma, Development of gelatin/ascorbic acid cryogels for potential use in corneal stromal tissue engineering, Acta Biomaterialia, 65 (2018) 123-136. doi:10.1016/j.actbio.2017.11.018
5. Q. Jiang, H. Liu, Q. Xiao, S.F. Chou, A.H. Xiong, H. Nie, Three-dimensional numerical simulation of total warpage deformation for fiber-reinforced polymer injection-molded parts using coupled FEM, Journal of Polymer Engineering, September (2018), accepted in press. doi:10.1515/polyeng-2016-0445
6. S.F. Chou, C.H. Lee, J.Y. Lai, Bioengineered keratocyte spheroids fabricated on chitosan coatings enhance tissue repair in a rabbit corneal stromal defect model, Journal of Tissue Engineering and Regenerative Medicine, 12 (2018) 316-320. doi:10.1002/term.2456
7. S.F. Chou, S. Gunaseelan, M.H.H. Kiellani, V.V.K. Thottempudi, P. Neuenschwander, H. Nie, A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing, Journal of Nanotechnology, 2017 (2017), Article ID 6341710, 15 pages. doi:10.1155/2017/6341710
8. S.F. Chou, L.J. Luo, J.Y. Lai, In vivo pharmacological evaluations of pilocarpine-loaded antioxidantfunctionalized biodegradable thermogels in glaucomatous rabbits, Scientific Reports, 7 (2017) 42344. doi:10.1038/srep42344
9. S.F. Chou, L.J. Luo, J.Y. Lai, D.H.K. Ma, Role of solvent-mediated carbodiimide cross-linking in fabrication of electrospun gelatin nanofibrous membranes as ophthalmic biomaterials, Materials Science and Engineering C: Materials for Biological Applications, 71 (2017) 1145-1155. doi:10.1016/j.msec.2016.11.105
10. S.F. Chou, K.A. Woodrow, Relationships between mechanical properties and drug release from electrospun fibers of PCL and PLGA blends, Journal of the Mechanical Behavior of Biomedical Materials, 65 (2017) 724-733. doi:10.1016/j.jmbbm.2016.09.004
11. S.F. Chou, L.J. Luo, J.Y. Lai, D.H.K Ma, On the importance of Bloom number of gelatin to the development of biodegradable in situ gelling copolymers for intracameral drug delivery, International Journal of Pharmaceutics, 511 (2016) 30-43. doi:10.1016/j.ijpharm.2016.06.129
12. S.F. Chou, L.J. Luo, J.Y. Lai, Gallic acid grafting effect on delivery performance and antiglaucoma efficacy of antioxidant-functionalized intracameral pilocarpine carriers, Acta Biomaterialia, 38 (2016) 116-128. doi:10.1016/j.actbio.2016.04.035
13. S.F. Chou, J.Y. Lai, C.H. Cho, C.H. Lee, Relationships between surface roughness/stiffness of chitosan coatings and fabrication of corneal keratocyte spheroids: effect of degree of deacetylation, Colloids and Surfaces B: Biointerfaces, 142 (2016) 105-113. doi:10.1016/j.colsurfb.2016.02.051
14. C. Ball, S.F. Chou, Y. Jiang, K.A. Woodrow, Coaxially electrospun fiber-based microbicides facilitate broadly tunable release of maraviroc, Materials Science and Engineering C: Materials for Biological Applications, 63 (2016) 117-124. doi:10.1016/j.msec.2016.02.018
15. C.C. Sun, S.F. Chou, J.Y. Lai, C.H. Cho, C.H. Lee, Dependence of corneal keratocyte adhesion, spreading, and integrin β1 expression on deacetylated chitosan coating, Materials Science and Engineering C: Materials for Biological Applications, 63 (2016) 222-230. doi:10.1016/j.msec.2016.02.069
16. S.F. Chou, D.C. Carson, K.A. Woodrow, Current strategies for sustaining drug release from electrospun nanofibers, Journal of Controlled Release, 220 (2015) 584-591. doi:10.1016/j.jconrel.2015.09.008
17. S.F. Chou, R.A. Overfelt, M.E. Miller, Anisotropic mechanical behavior of keratin tissue from quill shells of North American porcupine (Erethizon dorsatum), Materials Science and Engineering A, 557 (2012) 36-44. doi:10.1016/j.msea.2012.05.111
18. S.F. Chou, R.A. Overfelt, Tensile deformation and failure of North American porcupine quills, Materials Science and Engineering C: Materials for Biological Applications, 31 (2011) 1729-1736. doi:10.1016/j.msec.2011.08.002
19. S.F. Chou, W.F. Gale, H.S. Gale, C.G. Shannon, G. Buschle-Diller, N.I. Sofyan, Evaluation of airliner cabin textile materials after vapour phase hydrogen peroxide decontamination, Materials Science and Technology, 26 (2010) 66-80. doi:10.1179/174328408X378681
20. W.F. Gale, N.I. Sofyan, H.S. Gale, M.H. Sk, S.F. Chou, J.W. Fergus, C.G. Shannon, Effect of vapour phase hydrogen peroxide, as a decontaminant for civil aviation applications, on microstructure, tensile properties and corrosion resistance of 2024 and 7075 age hardenable aluminium alloys and 304 austenitic stainless steel, Materials Science and Technology, 25 (2009) 76-84. doi:10.1179/174328408X307256

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